Phytosome - more bioavailable

For good bioavailability, natural products must have a good balance between hydrophilicity (for dissolving into the gastro-intestinal fluids) and lipophilicity (to cross lipidic biomembranes). Many phytoconstituents like glycosilated polyphenolics have good water solubility, but are, nevertheless, poorly absorbed[1] because of their large size, incompatible with a process of passive diffusion and/or their poor miscibility with oils and other lipids. As a result, the ability of flavonoids to cross the lipid-rich outer membrane of small intestine enterocytes is severely limited.[2]